http://opendata.unex.es/recurso/ciencia-tecnologia/investigacion/publicaciones/Publicacion/2018-2828
Literals
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- @article{44276430cb4a4eec88c02ffe52663a14,
title = 'Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis',
abstract = 'Fronto-temporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two related and incurable neurodegenerative diseases. Features of these diseases include pathological protein inclusions in affected neurons with TAR DNA-binding protein 43 (TDP-43), dipeptide repeat proteins derived from the C9ORF72 gene, and fused in sarcoma (FUS) representing major constituent proteins in these inclusions. Mutations in C9ORF72 and the genes encoding TDP-43 and FUS cause familial forms of FTD/ALS which provides evidence to link the pathology and genetics of these diseases. A large number of seemingly disparate physiological functions are damaged in FTD/ALS. However, many of these damaged functions are regulated by signalling between the endoplasmic reticulum and mitochondria, and this has stimulated investigations into the role of endoplasmic reticulum-mitochondria signalling in FTD/ALS disease processes. Here, we review progress on this topic.',
author = 'Lau, {Dawn H.W.} and Naomi Hartopp and Welsh, {Natalie J.} and Sarah Mueller and Glennon, {Elizabeth B.} and M{\'o}rotz, {G{\'a}bor M.} and Ambra Annibali and Patricia Gomez-Suaga and Radu Stoica and Sebastien Paillusson and Miller, {Christopher C.J.}',
year = '2018',
month = mar,
day = '1',
doi = '10.1038/s41419-017-0022-7',
language = 'English',
volume = '9',
journal = 'Cell Death and Disease',
issn = '2041-4889',
publisher = 'Nature Publishing Group',
number = '3',
}
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- bibo:doi
- 10.1038/s41419-017-0022-7
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- ou:tipoPublicacion
- dcterms:title
- Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis
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Typed Literals