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- 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis in neural growth factor (NGF)-differentiated pheochromocytoma PC12 cells
- A dioxin-like compound induces hyperplasia and branching morphogenesis in mouse mammary gland, through alterations in TGF-β1 and aryl hydrocarbon receptor signaling
- A genetic polymorphism in coumarin 7-hydroxylation: Sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
- A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells
- A remarkable new target gene for the dioxin receptor: The Vav3 proto-oncogene links AhR to adhesion and migration
- Altered cell cycle control at the G<inf>2</inf>/M phases in aryl hydrocarbon receptor-null embryo fibroblast
- Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor
- Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor
- Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice
- Analysis of the selenocysteine (Sec) tRNA population in mouse embryonic stem (ES) cells heterozygous for the Sec tRNA gene
- Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK, and Wnt/β-Catenin Signaling
- Aryl Hydrocarbon Receptor: From Homeostasis to Tumor Progression
- Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells
- Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin
- Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice
- Aryl hydrocarbon receptor-dependent induction of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in cerebellar granule cells from mouse
- Aryl hydrocarbon receptor knockout mice (AHR(-/-)) exhibit liver retinoid accumulation and reduced retinoic acid metabolism
- Aryl hydrocarbon receptor deficient mice (Ahr-/-) exhibit an accumulation of liver retinylpalmitate
- Aryl hydrocarbon receptor controls skin homeostasis, regeneration, and hair follicle cycling by adjusting epidermal stem cell function
- Aryl hydrocarbon receptor blocks aging-induced senescence in the liver and fibroblast cells
- Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis
- Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity
- Assignment of the human dihydropyrimidine dehydrogenase gene (DPYD) to chromosome region 1p22 by fluorescence in situ hybridization
- Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch
- CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis
- CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice
- CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis
- Carcinogenesis of the food mutagen PhIP in mice is dependent of CYP1A2
- Characterization of the human dihydropyrimidine dehydrogenase gene
- Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374
- Correlation between catalytic activity and protein content for the polymorphically expressed dihydropyrimidine dehydrogenase in human lymphocytes
- DIAGNOSTIC-ANALYSIS, CLINICAL IMPORTANCE AND MOLECULAR-BASIS OF DIHYDROPYRIMIDINE DEHYDROGENASE-DEFICIENCY
- Differential regulation of mouse Ah receptor gene expression in cell lines of different tissue origins
- Differential scanning calorimetry study of glycogen phosphorylase b-detergent interactions
- Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects
- Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer
- Dioxin Receptor Adjusts Liver Regeneration After Acute Toxic Injury and Protects Against Liver Carcinogenesis
- Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch
- Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-β overexpression in the stroma
- Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition
- Dioxin receptor regulates aldehyde dehydrogenase to block melanoma tumorigenesis and metastasis
- Down-regulation of CYP1A2 induction during the maturation of mouse cerebellar granule cells in culture: Role of nitric oxide accumulation
- Effect of immobilization on the activity of rat hepatic microsomal cytochrome P450 enzymes
- Effect of phenobarbital on hepatic CYP1A1 and CYP1A2 in the Ahr-null mouse
- Effect of thioridazine dosage on the debrisoquine hydroxylation phenotype in psychiatric patients with different CYP2D6 genotypes
- Erratum: Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-κB (International Journal of Cancer (2005) 115 (74-84))
- Expression of CYP2A genes in human liver and extrahepatic tissues
- Fitting a xenobiotic receptor into cell homeostasis: How the dioxin receptor interacts with TGFβ signaling
- From Nucleus to Organs: Insights of Aryl Hydrocarbon Receptor Molecular Mechanisms
- Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy
- Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo
- Genomic instability in Gadd45a-deficient mice
- Hepatic fibrosis and cytochrome P450: Experimental models of fibrosis compared to AHR knockout mice
- Hepatic fibrosis in Ahr(-/-) mice
- Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish
- Human polymorphism in drug metabolism: Mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea
- Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism
- Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model
- Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
- Improving cancer therapeutics by molecular profiling
- L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke
- LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-β activity: Role of extracellular proteases plasmin and elastase
- Lack of correlation between phenotype and genotype for the polymorphically expressed dihydropyrimidine dehydrogenase in a family of Pakistani origin
- Lack of the aryl hydrocarbon receptor accelerates aging in mice
- Lesions of Aryl-hydrocarbon Receptor-deficient Mice
- Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-β-binding protein-1
- Liver regeneration after partial hepatectomy is improved in the absence of aryl hydrocarbon receptor
- Loss of aryl hydrocarbon receptor favors k-ras<sup>g12d</sup>-driven non-small cell lung cancer
- Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFβ
- Lung regeneration after toxic injury is improved in absence of dioxin receptor
- Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines
- Modulation of (Ca<sup>2+</sup> + Mg<sup>2+</sup>)-ATPases and Ca<sup>2+</sup> fluxes through the plasma membrane of synaptosomes and sarcoplasmic reticulum by local anaesthetics
- Modulation of the sarcoplasmic reticulum (Ca<sup>2+</sup> + Mg<sup>2+</sup>)-ATPase by pentobarbital
- Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity
- Mutations at codon 974 of the DPYD gene are a rare event
- Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2
- Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons
- New trends in Aryl hydrocarbon receptor biology
- Nomenclature for human DPYD alleles
- Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: Modulation of the phosphoinositide 3-kinase pathway
- Oculomotor Deficits in Aryl Hydrocarbon Receptor Null Mouse
- Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19
- Overexpression of latent transforming growth factor-β binding protein 1 (LTBP-1) in dioxin receptor-null mouse embryo fibroblasts
- PiRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice
- Piperonyl butoxide and acenaphthylene induce cytochrome P450 1A2 and 1B1 mRNA in aromatic hydrocarbon-responsive receptor knock-out mouse liver
- Polycyclic aromatic hydrocarbon-inducible DNA adducts: Evidence by <sup>32</sup>P-postlabeling and use of knockout mice for AH receptor-independent mechanisms of metabolic activation in vivo
- Potassium-induced apoptosis in rat cerebellar granule cells involves cell-cycle blockade at the G1/S transition
- Proteasome inhibition induces nuclear translocation and transcriptional activation of the dioxin receptor in mouse embryo primary fibroblasts in the absence of xenobiotics
- Proteasome inhibition induces nuclear translocation of the dioxin receptor through an Sp1 and protein kinase C-dependent pathway
- Pyrimidines and CNS regulation
- RNA-seq analysis to measure the expression of SINE retroelements
- Recruitment of CREB1 and Histone Deacetylase 2 (HDAC2) to the Mouse Ltbp-1 Promoter Regulates its Constitutive Expression in a Dioxin Receptor-dependent Manner
- Regulation of cell survival by resveratrol involves inhibition of NFκB-regulated gene expression in prostate cancer cells
- Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor α-dependent mechanism: Relevance in cell proliferation
- Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-κB
- Role of CYP2E1 in the hepatotoxicity of acetaminophen
- Role of transforming growth factor β in cancer microenvironment
- Selenocysteine tRNA([Ser]Sec) levels and selenium-dependent glutathione peroxidase activity in mouse embryonic stem cells heterozygous for a targeted mutation in the tRNA([Ser]Sec) gene
- Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor
- Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12- dimethylbenz[a]anthracene
- Targeted disruption of the α isoform of the peroxisome proliferator- activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
- Targeted disruption of specific cytochromes P450 and xenobiotic receptor genes
- Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development
- The AHR Regulates Cell Adhesion and Migration by Interacting with Oncogene and Growth Factor-Dependent Signaling
- The Ah Receptor from Toxicity to Therapeutics: Report from the 5th AHR Meeting at Penn State University, USA, June 2022
- The Dioxin receptor modulates Caveolin-1 mobilization during directional migration: Role of cholesterol
- The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
- The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: Cell-specific alteration of the cell cycle
- The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein
- The aryl hydrocarbon receptor. Studies using the AHR-null mice
- The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value
- The aryl hydrocarbon receptor promotes differentiation during mouse preimplantational embryo development
- The dioxin receptor regulates the constitutive expression of the Vav3 proto-oncogene and modulates cell shape and adhesion
- The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis
- The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway
- The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding
- The involvement of aryl hydrocarbon receptor in the activation of transforming growth factor-β and apoptosis
- The role of the aryl hydrocarbon receptor in animal development, physiological homeostasis and toxicity of TCDD
- Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype
- Transcriptional factor Aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene
- Transcriptional induction of the cytochrome P4501A1 gene by a thiazolium compound, YH439
- Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms
- Xenobiotic receptor knockout mice
- cDNA cloning and chromosome mapping of human dihydropyrimidine dehydrogenase, an enzyme associated with 5-fluorouracil toxicity and congenital thymine uraciluria
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