JOSÉ JAVIER LÓPEZ BARBA

Literals

• foaf:lastName
  • LÓPEZ BARBA
• foaf:firstName
  • JOSÉ JAVIER
• ou:categoriaPDI
  • 00063-PROFESOR CONTRATADO DOCTOR
• ou:dedicacionPDI
  • TIEMPO COMPLETO
• aiiso:code
  • 94c3a6470e4d2bc61c690d20fdeb9190
• ou:dialnetId
  • 2423259
• ou:indiceHscopus
  • 31
• foaf:name
  • JOSÉ JAVIER LÓPEZ BARBA
• vivo:orcidId
  • 0000000252341478
• ou:orcidURL
  • http://orcid.org/0000000252341478
• vivo:scopusId
  • 55685083400

Typed Literals

• ou:esDoctor
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• ou:personalActual
  • True (xsd:boolean)

Relations

• teach:teacherOf
  • ENDOCRINOLOGÍA MOLECULAR
  • ACTIVIDADES FÍSICAS EN PERSONAS CON PROBLEMAS DE SALUD CRÓNICOS: NEUROMUSCULARES, RESPIRATORIAS, DOL
  • ACTIVIDADES FÍSICAS PERSONAS PROBLEMAS SALUD CRÓNICOS: NEUROMUSCULARES, RESPIRATORIAS, DOLOR, CANCER
  • ACTIVIDADES FÍSICAS PERSONAS PROBLEMAS SALUD CRÓNICOS: NEUROMUSCULARES, RESPIRATORIAS, DOLOR, CANCER
  • ENDOCRINOLOGÍA MOLECULAR
  • ENDOCRINOLOGÍA Y REGULACIÓN METABÓLICA
  • ENDOCRINOLOGÍA Y REGULACIÓN METABÓLICA
  • FISIOLOGÍA HUMANA
  • FISIOLOGÍA HUMANA
  • FISIOLOGÍA HUMANA
  • HEMATOLOGÍA Y HEMOTERAPIA
  • HEMATOLOGÍA Y HEMOTERAPIA
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• ou:tienePublicacion
  • (−)‑Oleocanthal inhibits proliferation and migration by modulating Ca²⁺ entry through TRPC6 in breast cancer cells
  • A fibrin coating method of polypropylene meshes enables the adhesion of menstrual blood-derived mesenchymal stromal cells: A new delivery strategy for stem cell-based therapies
  • Acidic NAADP-releasable Ca2+ compartments in the megakaryoblastic cell line MEG01
  • Adenylyl cyclase type 8 overexpression impairs phosphorylation-dependent orai1 inactivation and promotes migration in MDA-MB-231 breast cancer cells
  • Antiaggregant effects of Arbutus unedo extracts in human platelets
  • Apelin: an antithrombotic factor that inhibits platelet function
  • Arachidonic acid attenuates cell proliferation, migration and viability by a mechanism independent on calcium entry
  • Attenuated store-operated divalent cation entry and association between STIM1, Orai1, hTRPC1 and hTRPC6 in platelets from type 2 diabetic patients
  • Axial stretch-dependent cation entry in dystrophic cardiomyopathy: Involvement of several TRPs channels
  • Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: A new aspect in therapy of cardiovascular diseases
  • Ca²⁺ accumulation into acidic organelles mediated by Ca ²⁺- and vacuolar H⁺-ATPases in human platelets
  • Cardiovascular and hemostatic disorders: SOCE and Ca²⁺ handling in platelet dysfunction
  • Cardiovascular system SOCE and Ca²⁺ handling in platelet dysfunction
  • Caspase-3 and -9 are activated in human myeloid HL-60 cells by calcium signal
  • Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor
  • Correction to: Orai2 Modulates Store-Operated Ca2+ Entry and Cell Cycle Progression in Breast Cancer Cells (Cancers, (2021), 14, 1, (114), 10.3390/cancers14010114)
  • Cross-Talk Between the Adenylyl Cyclase/cAMP Pathway and Ca²⁺ Homeostasis
  • Crucial role for endoplasmic reticulum stress during megakaryocyte maturation
  • Cytoskeletal and scaffolding proteins as structural and functional determinants of TRP channels
  • Data from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Data from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Data on calcium increases depending on stretch in dystrophic cardiomyocytes
  • Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry
  • EFHB is a novel cytosolic Ca ²⁺ sensor that modulates STIM1-SARAF interaction
  • ELA/APELA precursor cleaved by furin displays tumor suppressor function in renal cell carcinoma through mTORC1 activation
  • Early caspase-3 activation independent of apoptosis is required for cellular function
  • Enhanced expression of STIM1/Orai1 and TRPC3 in platelets from patients with type 2 diabetes mellitus
  • Feedback modulation of Orai1α and Orai1β protein content mediated by STIM proteins
  • Figures S1-S4 from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Figures S1-S4 from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Filamin A Modulates Store-Operated Ca²⁺ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets
  • Filamin A modulates platelet function
  • Fine-tuning of store-operated calcium entry by fast and slow Ca²⁺-dependent inactivation: Involvement of SARAF
  • Flavonoids and platelet-derived thrombotic disorders
  • Functional differences in agonist-induced plasma membrane expression of Orai1α and Orai1β
  • Functional relevance of the de novo coupling between hTRPC1 and type II IP<inf>3</inf> receptor in store-operated Ca²⁺ entry in human platelets
  • Functional role of TRPC6 and STIM2 in cytosolic and endoplasmic reticulum Ca²⁺ content in resting estrogen receptor-positive breast cancer cells
  • Furin Prodomain Ppfurin Enhances Soce Through trpc6 Activation in Breast Cancer Cells
  • Furin prodomain ppfurin enhances ca²⁺ entry through orai and trpc6 channels’ activation in breast cancer cells
  • Historical overview of store-operated Ca²⁺ entry
  • Homer proteins in Ca²⁺ entry
  • Homocysteine induces caspase activation by endoplasmic reticulum stress in platelets from type 2 diabetics and healthy donors
  • Inactivation of proprotein convertases in T cells inhibits PD-1 expression and creates a favorable immune microenvironment in colorectal cancer
  • Interaction of STIM1 with endogenously expressed human canonical TRP1 upon depletion of intracellular Ca²⁺ stores
  • Intracellular Ca²⁺ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP<inf>3</inf> receptor and SERCA3 in human platelets
  • Intracellular Ca²⁺ homeostasis and aggregation in platelets are impaired by ethanol through the generation of H<inf>2</inf>O<inf>2</inf> and oxidation of sulphydryl groups
  • Intracellular Calcium Release from Human Platelets: Different Messengers for Multiple Stores
  • Involvement of stanniocalcins in the deregulation of glycaemia in obese mice and type 2 diabetic patients
  • Melatonin, as an adjuvant-like agent, enhances platelet responsiveness
  • Molecular Basis and Regulation of Store-Operated Calcium Entry
  • Molecular modulators of store-operated calcium entry
  • N,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine induces apoptosis through the activation of caspases-3 and -8 in human platelets. A role for endoplasmic reticulum stress
  • New insights into adipokines as potential biomarkers for type-2 diabetes mellitus
  • Orai1 mediates the interaction between STIM1 and hTRPC1 and regulates the mode of activation of hTRPC1-forming Ca²⁺ channels
  • Orai1α and Orai1β support calcium entry and mammosphere formation in breast cancer stem cells
  • Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells
  • Orai2 modulates store-operated ca²⁺ entry and cell cycle progression in breast cancer cells
  • Pharmacology of TRP channels in the vasculature
  • Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway
  • Postbiotics of Lacticaseibacillus paracaseiCECT 9610 and Lactiplantibacillus plantarumCECT 9608 attenuates store‐operated calcium entry and FAK phosphorylation in colorectal cancer cells
  • Role of Orai-family channels in the activation and regulation of transcriptional activity
  • Role of STIM1 in the surface expression of SARAF
  • Role of intracellular calcium on hydrogen peroxide-induced apoptosis in rat pancreatic acinar AR42J cells
  • Role of mTOR1 and mTOR2 complexes in MEG-01 cell physiology
  • Role of orai3 in the pathophysiology of cancer
  • SARAF modulates TRPC1, but not TRPC6, channel function in a STIM1-independent manner
  • SERCA2a controls the mode of agonist-induced intracellular Ca²⁺ signal, transcription factor NFAT and proliferation in human vascular smooth muscle cells
  • STIM1 and STIM2 are located in the acidic Ca²⁺ stores and associates with Orai1 upon depletion of the acidic stores in human platelets
  • STIM1 regulates acidic Ca²⁺ store refilling by interaction with SERCA3 in human platelets
  • Saraf and efhb modulate store-operated ca²⁺ entry and are required for cell proliferation, migration and viability in breast cancer cells
  • Similarities and Differences between the Orai1 Variants: Orai1α and Orai1β
  • Store-Operated Calcium Entry and Its Implications in Cancer Stem Cells
  • Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation
  • Store-independent Orai1-mediated Ca ²⁺ entry and cancer
  • Store-operated Ca ²⁺ entry in breast cancer cells: Remodeling and functional role
  • Store-operated Ca²⁺ entry is sensitive to the extracellular Ca²⁺ concentration through plasma membrane STIM1
  • Store-operated Ca²⁺ entry- Associated regulatory factor (SARAF) plays an important role in the regulation of arachidonate-regulated Ca²⁺ (ARC) channels
  • Supplementary Materials and Methods from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Supplementary Materials and Methods from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Supplementary Table S1 from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Supplementary Table S1 from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Supplementary Table S2 from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Supplementary Table S2 from Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer
  • Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca²⁺-ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells
  • TRPC channels in the SOCE scenario
  • TRPC3 regulates agonist-stimulated Ca²⁺ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1
  • TRPC6 participates in the regulation of cytosolic basal calcium concentration in murine resting platelets
  • TRPs in pain sensation
  • The Ca²⁺ Sensor STIM in Human Diseases
  • The orai1-ac8 interplay: How breast cancer cells escape from orai1 channel inactivation
  • The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium
  • The store-operated Ca²⁺ channel Orai1α is required for agonist-evoked NF-κB activation by a mechanism dependent on PKCβ2
  • Thrombin induces activation and translocation of Bid, Bax and Bak to the mitochondria in human platelets
  • Thrombin induces apoptotic events through the generation of reactive oxygen species in human platelets
  • Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca²⁺ entry by regulation of STIM1-Orai1 association
  • Trpc6 channels are required for proliferation, migration and invasion of breast cancer cell lines by modulation of orai1 and orai3 surface exposure
  • Two distinct Ca²⁺ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets
  • Two pathways for store-mediated calcium entry differentially dependent on the actin cytoskeleton in human platelets
  • Two-pore channel 2 (TPC2) modulates store-operated Ca²⁺ entry
  • Tyrosine phosphorylation/dephosphorylation balance is involved in thrombin-evoked microtubular reorganisation in human platelets
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• ou:perteneceAGrupoInvestigacion
  • FISIOLOGIA CELULAR
• ou:adscritoADepartamento
  • FISIOLOGÍA
• ou:imparteDocenciaEnArea
  • FISIOLOGÍA
• ou:adscritoACentro
  • Facultad De Veterinaria

Inverse Relations

• Has related: ou:autorTesis
  • Relación Entre La Señal De Calcio, Especies Reactivas De Oxígeno Y Apoptosis En Plaquetas Humanas
• Has related: ou:directorTesis
  • Estudio Del Remodelado De La Homeostasis Del Calcio Intracelular En Las Células De Cáncer De Mama
  • Papel De Los Canales Trpc6 Y Trpa1 En La Homeostasis Del Ca2+ Intracelular

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    • swrcfe:role Investigador
    • swrcfe:project ESTUDIO DEL PAPEL DE LAS VARIANTES DEL CANAL ORAI 1, ORAI 1 ALFA Y ORAI 1 BETA, EN LA FUNCIÓN CELULAR.
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    • swrcfe:project REMODELADO DE LA EXPRESIÓN DE STIM Y ORAI Y DE SUS MECANISMOS REGULADORES EN EL CÁNCER DE MAMA
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    • swrcfe:role Investigador
    • swrcfe:project RELEVANCIA DE LOS CANALES ORAI EN LAS CARACTERÍSTICAS Y PROGRESIÓN DEL CÁNCER DE MAMA
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  • [Anonymous resource (nodeID://b7721615)
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    • swrcfe:project ESTUDIO DE LA INTERRELACIÓN DE LAS VARIANTES ALTERNATIVAS DE ORAI1 Y TRPC1 Y DE LAS CARACTERISTICAS FUNCIONALES DE LOS CANALES CAPACITATIVOS FORMADOS. RELEVANCIA EN LA FISIOPATOLOGIA DEL CÁNCER DE MAMA.
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    • swrcfe:role Investigador
    • swrcfe:project AYUDA AL GRUPO DE INVESTIGACIÓN DENOMINADO "FISIOLOGIA CELULAR"
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    • swrcfe:project ADQUISICIÓN DE UN SISTEMA DE VIDEOMICROSCOPÍA PARA CULTIVO CELULAR 3D.
    ]
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