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- ABCB1 polymorphisms are associated with cyclosporine-induced nephrotoxicity and gingival hyperplasia in renal transplant recipients
- Acetylator Polymorphism in Human Colorectal Carcinoma
- Acetylator polymorphism in Parkinson's disease
- Acetylator polymorphism in Alzheimer's disease
- Acetylator polymorphism in multiple sclerosis
- Acetylator polymorphism in rheumatoid arthritis
- Action COST B15: Modelling during drug development - October 1998 to July 2004
- Acute Effects of 1‐Methyl‐4‐Phenyl‐1, 2, 3, 6‐Tetrahydropyridine in a Model of Rat Designated a Poor Metabolizer of Debrisoquine
- Adinosine triphosphate-binding cassette B1 (ABCB1) (multidrug resistance 1) G2677T/A gene polymorphism is associated with high risk of lung cancer
- Aminopyrine N-demethylase activity in human liver microsomes
- Aminopyrine metabolism in man: The acetylation of aminoantipyrine cosegregates with acetylation of caffeine
- Analysis of midazolam and metabolites in plasma by high-performance liquid chromatography: Probe of CYP3A
- Applicability of an Assay for Routine Monitoring of Highly Variable Concentrations of Olanzapine Based on HPLC with Mass Spectrometric Detection
- Approach to therapeutic habits in extremadura: Diabetes
- Are antipsychotic drugs potentially chemopreventive agents for cancer?
- Assessment of the debrisoquin and dextromethorphan phenotyping tests by gaussian mixture distributions analysis
- Association between the oxidative polymorphism and early onset of Parkinson's disease
- Biodisponiblidad oral y de formulaciones farmacéuticas de Carbamazepina y su metabolito en voluntarios sanos
- C282Y and H63D mutations of HFE gene in patients with advanced alcoholic liver disease
- CYP1A1 gene polymorphisms increase lung cancer risk in a high-incidence region of Spain: A case control study
- CYP1A2 activity, gender and smoking, as variables influencing the toxicity of caffeine
- CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis
- CYP2C83 polymorphism and donor age are associated with allograft dysfunction in kidney transplant recipients treated with calcineurin inhibitors
- CYP2D6 genes and risk of liver cancer
- CYP2D6 genotypes in Spanish women with breast cancer
- CYP2D6, NAT2 and CYP2E1 genetic polymorphisms in nonagenarians
- Caffeine demethylase activity in human and Dark Agouti rat liver microsomes: Comparison with aminopyrine N-demethylase activity
- Caffeine metabolism in a healthy Spanish population: N-acetylator phenotype and oxidation pathways
- Changes Induced by Ovariectomy on the Acute Effects of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine in a Model of Rat Poor Metabolizer of Debrisoquine
- Clinically significant pharmacokinetic interactions between dietary caffeine and medications
- Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test.
- Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H<inf>2</inf>-receptor antagonists
- DEBRISOQUINE HYDROXYLATION PHENOTYPES IN HEALTHY VOLUNTEERS
- Debrisoquin oxidation genotype and susceptibility to lung cancer
- Debrisoquin oxidation polymorphism in a Spanish population
- Debrisoquine oxidation phenotype in psychiatric patients.
- Debrisoquine oxidation in an Italian population: A study in healthy subjects and in schizophrenic patients
- Debrisoquine oxidation polymorphism in patients with rheumatoid arthritis [1]
- Debrisoquine oxidation in schizophrenic patients treated with neuroleptics
- Debrisoquine oxidation phenotype during neuroleptic monotherapy
- Debrisoquine oxidation phenotype during neuroleptic monotherapy
- Debrisoquine oxidation polymorphism in patients with chronic inflammatory bowel disease
- Debrisoquine polymorphism: mechanism for very rapid oxidative phenotype
- Determination of aminopyrine and dipyrone metabolites in urine [2]
- Determination of aminopyrine, dipyrone and its metabolites in urine by high-performance liquid chromatography
- Differences in CYP3A5*3 genotype distribution and combinations with other polymorphisms between Spaniards and other Caucasian populations
- Differences in antidiabetic drug utilisation between three different health systems in the same national region
- Early detection of drug interactions utilizing a computerized drug prescription handling system - Focus on cerivastatin-gemfibrozil
- Effect of common NAT2 variant alleles in the acetylation of the major clonazepam metabolite, 7-aminoclonazepam.
- Effect of neurotransmitters on NADPH-cytochrome P450 reductase in vitro activity.
- Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients
- Evaluation of a drug-drug interaction alert structure through the retrospective analysis of statins-macrolides co-prescriptions
- Evaluation of caffeine as an in vivo probe for CYP1A2 using measurements in plasma, saliva, and urine
- Expression in human prostate of drug- and carcinogen-metabolizing enzymes: Association with prostate cancer risk
- Farmacogenética
- Frequency of CYP2D6 allelic variants in multiple sclerosis
- Frequency of S-mephenytoin hydroxylation deficiency in 373 spanish subjects compared to other Caucasian populations
- Functionally active duplications of the CYP2D6 gene are more prevalent among larynx and lung cancer patients
- GST polymorphisms interact with dietary factors to modulate lung cancer risk: Study in a high-incidence area
- Genetic analysis of the NAT2 and CYP2D6 polymorphisms in white patients with non-insulin-dependent diabetes mellitus
- Genetic analysis of the arylamine N-acetyltransferase polymorphism in breast cancer patients
- Genetic basis for differences in debrisoquin polymorphism between a Spanish and other white populations
- Genetic polymorphism in drug oxidative metabolism
- Haplotypes in the 5′-untranslated region of the CYP1A2gene are inversely associated with lung cancer risk but do not correlate with caffeine metabolism
- Identification and characterisation of novel polymorphisms in the CYP2A locus: Implications for nicotine metabolism
- Identification and prevalence study of 17 allelic variants of the human NAT2 gene in a white population
- Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation
- Increased frequency of rapid acetylator genotypes in patients with brain astrocytoma and meningioma
- Increased risk for hepatocellular carcinoma in NAT2-slow acetylators and CYP2D6-rapid metabolizers
- Influence of genetic admixture on polymorphisms of drug-metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic population
- Inhibition of cytochrome P450 2C9 activity in vitro by 5-hydroxytryptamine and adrenaline
- Interaction between prajmaline and metoprotol: a possible pharmacogenetic explanation
- Interethnic differences in drug metabolism: Influence of genetic and environmental factors on debrisoquine hydroxylation phenotype
- Key Learning Outcomes for Clinical Pharmacology and Therapeutics Education in Europe: A Modified Delphi Study
- Lung cancer and mutations at the polymorphic NAT2 gene locus
- Metabolism of aminopyrine and derivatives in man: In vivo study of monomorphic and polymorphic metabolic pathways
- Modulation of CYP1A2 enzyme activity by indoleamines: Inhibition by serotonin and tryptamine
- Modulation of midazolam 1-hydroxylation activity in vitro by neurotransmitters and precursors
- Molecular analysis of the arylamine N-acetyltransferase polymorphism in a Spanish population
- Molecular heterogeneity at the CYP2D gene locus in Nicaraguans: Impact of gene-flow from Europe
- Mutaciones C282Y y H63D del gen HFE en pacientes con hepatopatía alcohólica avanzada
- N-acetyltransferase 2 polymorphism is not related to the risk of advanced alcoholic liver disease
- N-acetyltransferase 2 (NAT2) genotype and colorectal carcinoma: Risk variability according to tumour site?
- N-acetyltransferase 2 single-nucleotide polymorphisms and risk of gastric carcinoma
- Obliterative bronchiolitis with idiopathic organizing pneumonia. Report of 2 cases
- Oxidative polymorphism of debrisoquine is not related to human colo-rectal cancer
- Oxidative polymorphism of debrisoquine is not related to the risk of Alzheimer's disease
- Oxidative polymorphism of debrisoquine in Parkinson's disease
- Pharmacogenetic testing and therapeutic drug monitoring are complementary tools for optimal individualization of drug therapy
- Pharmacogenetics in clinical pharmacology: Present and future
- Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients
- Pharmacokinetic-pharmacodynamic modelling of the antipyretic effect of two oral formulations of ibuprofen
- Plasma concentrations of nortriptyline and its 10‐hydroxy metabolite in depressed patients‐relationship to the debrisoquine hydroxylation metabolic ratio.
- Polimorfismo acetilador en el cancer de pulm6n
- Polimorfismos enzimáticos y cáncer de pulmón
- Polymorphic oxidation of debrisoquine in lung cancer patients
- Polymorphic oxidation of debrisoquine in women with breast cancer
- Polymorphic oxidation of debrisoquine in bladder cancer
- Polymorphism is not associated with essential tremor
- Possible implications of doxycycline-rifampin interaction for treatment of brucellosis
- Potential role of cerebral cytochrome P450 in clinical pharmacokinetics: Modulation by endogenous compounds
- Preparing a personal formulary as part of a course in clinical pharmacology
- Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population
- Relationship between personality and debrisoquine hydroxylation capacity: Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6
- Relevancia de los polimorfismos genéticos en la respuesta farmacológica
- Reproducibility over Time of Mephenytoin and Debrisoquine Hydroxylation Phenotypes
- Retinal toxic reactions following photopheresis
- Role of the smoking-induced cytochrome P450 (CYP)1A2 and polymorphic CYP2D6 in steady-state concentration of olanzapine
- Rsa I polymorphism at the cytochrome P4502E1 locus is not related to the risk of alcohol-related severe liver disease
- RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma
- Sex and age-related differences in aminopyrine n-demethylase activity in DA- and wistar-strain rat liver microsomes. Effect of ovariectomy
- Single nucleotide polymorphisms and microsatellite alleles of tumor necrosis factor alpha and interleukin-10 genes and the risk of advanced chronic alcoholic liver disease
- Slow allotypic variants of the NAT2 gene and susceptibility to early- onset Parkinson's disease
- The effect of CYP2J2, CYP3A4, CYP3A5 and the MDR1 C3435T polymorphisms and gender on the urinary excretion of the metabolites of the H<inf>1</inf>-receptor antihistamine ebastine: A pilot study
- Therapeutic information centers: Coordination and information
- Thioether excretion, urinary mutagenicity
- Tryptamine: A possible endogenous substrate for CYP2D6
- Unified report from committees on ethics and clinical investigations in multicenter trials
- Urinary bladder cancer in a girl with a slow-acetylator genotype and treated with sulphasalazine
- Use of antigout drugs in Extremadura
- Use of antimigraine drugs in extremadura
- Use of the mesoridazine/thioridazine ratio as a marker for CYP2D6 enzyme activity
- Using a computerized drug prescription screening system to trace drug interactions in an outpatient setting
- Viral myocarditis. A report of a case and literature review
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