PUBLICACIÓN

Hyperhaemolysis syndrome responsive to splenectomy in a patient with δβ-thalassaemia: A discussion on underlying mechanisms

ACCEDER A LA PUBLICACIÓN: Scopus Orcid

Vagace J.M., Casado M.S., Bajo R., Gervasini G.

2014 Blood Transfusion

Hematology (Q3), Immunology and Allergy (Q3), Medicine (miscellaneous) (Q2)

JCR: 2.372

SJR: 0.501

CITAS

5

DOI

10.2450/2013.0059-13

EID

2-s2.0-84894184972

ISSN

1723-2007

BIBTEX

@article{PMID:24333072, title = {Hyperhaemolysis syndrome responsive to splenectomy in a patient with δβ-thalassaemia: a discussion on underlying mechanisms.}, author = {Vagace JM and Casado MS and Bajo R and Gervasini G}, doi = {10.2450/2013.0059-13}, journal = {Blood transfusion = Trasfusione del sangue}, month = {01}, year = {2014} }

AUTORES DE LA UEX

Guillermo Gervasini Rodríguez
José Manuel Vagace Valero

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Impact Of Negr1 Genetic Variability On Psychological Traits Of Patients With Eating Disorders
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Clinical Relevance Of Erythrocyte Ferritin In Microcytic Anemias
Melanocortin-4 Receptor Gene Variants Are Not Associated With Binge-Eating Behavior In Nonobese Patients With Eating Disorders
Impact Of Negr1 Genetic Variability On Psychological Traits Of Patients With Eating Disorders.
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Impact Of Negr1 Genetic Variability On Psychological Traits Of Patients With Eating Disorders.
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Impact Of Negr1 Genetic Variability On Psychological Traits Of Patients With Eating Disorders.
Thalassemia Diagnosis In A Blood Donor From A Unique Trimorphic Red Blood Cell Population Observed In The Recipient
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Thalassemia Diagnosis In A Blood Donor From A Unique Trimorphic Red Blood Cell Population Observed In The Recipient
Hyperhaemolysis Syndrome Responsive To Splenectomy In A Patient With Δβ-Thalassaemia: A Discussion On Underlying Mechanisms
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Hyperhaemolysis Syndrome Responsive To Splenectomy In A Patient With Δβ-Thalassaemia: A Discussion On Underlying Mechanisms
Bdnf Genetic Variability Modulates Psychopathological Symptoms In Patients With Eating Disorders
Diagnostic And Therapeutic Challenges Of Primary Autoimmune Haemolytic Anaemia In Children
Bdnf Genetic Variability Modulates Psychopathological Symptoms In Patients With Eating Disorders
Diagnostic And Therapeutic Challenges Of Primary Autoimmune Haemolytic Anaemia In Children
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Diagnostic And Therapeutic Challenges Of Primary Autoimmune Haemolytic Anaemia In Children
Novel Variants In The Mc4r And Lepr Genes Among Severely Obese Children From The Iberian Population
Bdnf Genetic Variability Modulates Psychopathological Symptoms In Patients With Eating Disorders.
Novel Variants In The Mc4r And Lepr Genes Among Severely Obese Children From The Iberian Population
Bdnf Genetic Variability Modulates Psychopathological Symptoms In Patients With Eating Disorders.
Hyperhaemolysis Syndrome Responsive To Splenectomy In A Patient With Δβ-Thalassaemia: A Discussion On Underlying Mechanisms.
Bdnf Genetic Variability Modulates Psychopathological Symptoms In Patients With Eating Disorders.
Hyperhaemolysis Syndrome Responsive To Splenectomy In A Patient With Δβ-Thalassaemia: A Discussion On Underlying Mechanisms.
Relevancia De Los Polimorfismos Genéticos En La Respuesta Farmacológica
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Relevancia De Los Polimorfismos Genéticos En La Respuesta Farmacológica
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Diagnostic Utility Of Hfe Variants In Spanish Patients: Association With Hla Alleles And Role In Susceptibility To Acute Lymphoblastic Leukemia
Comparative Cytochrome P450 In Vitro Inhibition By Atypical Antipsychotic Drugs.
Diagnostic Utility Of Hfe Variants In Spanish Patients: Association With Hla Alleles And Role In Susceptibility To Acute Lymphoblastic Leukemia
Comparative Cytochrome P450 In Vitro Inhibition By Atypical Antipsychotic Drugs.
Diagnostic Utility Of Hfe Variants In Spanish Patients: Association With Hla Alleles And Role In Susceptibility To Acute Lymphoblastic Leukemia.
Comparative Cytochrome P450 In Vitro Inhibition By Atypical Antipsychotic Drugs.
Diagnostic Utility Of Hfe Variants In Spanish Patients: Association With Hla Alleles And Role In Susceptibility To Acute Lymphoblastic Leukemia.
Haplotypes In The 5'-Untranslated Region Of The Cyp1a2 Gene Are Inversely Associated With Lung Cancer Risk But Do Not Correlate With Caffeine Metabolism.
Diagnostic Utility Of Hfe Variants In Spanish Patients: Association With Hla Alleles And Role In Susceptibility To Acute Lymphoblastic Leukemia.
Haplotypes In The 5'-Untranslated Region Of The Cyp1a2 Gene Are Inversely Associated With Lung Cancer Risk But Do Not Correlate With Caffeine Metabolism.
Abcb1 Polymorphisms Are Associated With Cyclosporine-Induced Nephrotoxicity And Gingival Hyperplasia In Renal Transplant Recipients.
Haplotypes In The 5'-Untranslated Region Of The Cyp1a2 Gene Are Inversely Associated With Lung Cancer Risk But Do Not Correlate With Caffeine Metabolism.
Abcb1 Polymorphisms Are Associated With Cyclosporine-Induced Nephrotoxicity And Gingival Hyperplasia In Renal Transplant Recipients.
Toward A Clinical Practice Guide In Pharmacogenomics Testing For Functional Polymorphisms Of Drug-Metabolizing Enzymes. Gene/drug Pairs And Barriers Perceived In Spain
Abcb1 Polymorphisms Are Associated With Cyclosporine-Induced Nephrotoxicity And Gingival Hyperplasia In Renal Transplant Recipients.
Toward A Clinical Practice Guide In Pharmacogenomics Testing For Functional Polymorphisms Of Drug-Metabolizing Enzymes. Gene/drug Pairs And Barriers Perceived In Spain
Impact Of Genetic Polymorphisms On Chemotherapy Toxicity In Childhood Acute Lymphoblastic Leukemia
Toward A Clinical Practice Guide In Pharmacogenomics Testing For Functional Polymorphisms Of Drug-Metabolizing Enzymes. Gene/drug Pairs And Barriers Perceived In Spain
Impact Of Genetic Polymorphisms On Chemotherapy Toxicity In Childhood Acute Lymphoblastic Leukemia
Central Nervous System Chemotoxicity During Treatment Of Pediatric Acute Lymphoblastic Leukemia/lymphoma
Impact Of Genetic Polymorphisms On Chemotherapy Toxicity In Childhood Acute Lymphoblastic Leukemia
Central Nervous System Chemotoxicity During Treatment Of Pediatric Acute Lymphoblastic Leukemia/lymphoma
Polymorphisms In Serotonergic Genes And Psychopathological Traits In Eating Disorders
Central Nervous System Chemotoxicity During Treatment Of Pediatric Acute Lymphoblastic Leukemia/lymphoma
Polymorphisms In Serotonergic Genes And Psychopathological Traits In Eating Disorders
Impact Of Genetic Polymorphisms On Tacrolimus Pharmacokinetics And The Clinical Outcome Of Renal Transplantation
Polymorphisms In Serotonergic Genes And Psychopathological Traits In Eating Disorders
Impact Of Genetic Polymorphisms On Tacrolimus Pharmacokinetics And The Clinical Outcome Of Renal Transplantation
A Neutron Diagnostic For High Current Deuterium Beams.
Impact Of Genetic Polymorphisms On Tacrolimus Pharmacokinetics And The Clinical Outcome Of Renal Transplantation
A Neutron Diagnostic For High Current Deuterium Beams.
N-Acetyltransferase-2 (Nat2) Gene Polymorphisms And Enzyme Activity In Serbs: Unprecedented High Prevalence Of Rapid Acetylators In A White Population
A Neutron Diagnostic For High Current Deuterium Beams.
N-Acetyltransferase-2 (Nat2) Gene Polymorphisms And Enzyme Activity In Serbs: Unprecedented High Prevalence Of Rapid Acetylators In A White Population
Methotrexate-Induced Subacute Neurotoxicity In A Child With Acute Lymphoblastic Leukemia Carrying Genetic Polymorphisms Related To Folate Homeostasis
N-Acetyltransferase-2 (Nat2) Gene Polymorphisms And Enzyme Activity In Serbs: Unprecedented High Prevalence Of Rapid Acetylators In A White Population
Methotrexate-Induced Subacute Neurotoxicity In A Child With Acute Lymphoblastic Leukemia Carrying Genetic Polymorphisms Related To Folate Homeostasis
Variability Of The L-Histidine Decarboxylase Gene In Allergic Rhinitis
Methotrexate-Induced Subacute Neurotoxicity In A Child With Acute Lymphoblastic Leukemia Carrying Genetic Polymorphisms Related To Folate Homeostasis
Variability Of The L-Histidine Decarboxylase Gene In Allergic Rhinitis
Cyp1a1 Gene Polymorphisms Increase Lung Cancer Risk In A High-Incidence Region Of Spain: A Case Control Study
Variability Of The L-Histidine Decarboxylase Gene In Allergic Rhinitis
Cyp1a1 Gene Polymorphisms Increase Lung Cancer Risk In A High-Incidence Region Of Spain: A Case Control Study
Pharmacogenetic Testing And Therapeutic Drug Monitoring Are Complementary Tools For Optimal Individualization Of Drug Therapy
Cyp1a1 Gene Polymorphisms Increase Lung Cancer Risk In A High-Incidence Region Of Spain: A Case Control Study
Pharmacogenetic Testing And Therapeutic Drug Monitoring Are Complementary Tools For Optimal Individualization Of Drug Therapy
Gst Polymorphisms Interact With Dietary Factors To Modulate Lung Cancer Risk: Study In A High-Incidence Area
Pharmacogenetic Testing And Therapeutic Drug Monitoring Are Complementary Tools For Optimal Individualization Of Drug Therapy
Gst Polymorphisms Interact With Dietary Factors To Modulate Lung Cancer Risk: Study In A High-Incidence Area
Cyp2w1 Variant Alleles In Caucasians And Association Of The Cyp2w1 G541a (Ala181thr) Polymorphism With Increased Colorectal Cancer Risk
Gst Polymorphisms Interact With Dietary Factors To Modulate Lung Cancer Risk: Study In A High-Incidence Area
Cyp2w1 Variant Alleles In Caucasians And Association Of The Cyp2w1 G541a (Ala181thr) Polymorphism With Increased Colorectal Cancer Risk
In Vivo Evaluation Of Cyp2a6 And Xanthine Oxidase Enzyme Activities In The Serbian Population
Cyp2w1 Variant Alleles In Caucasians And Association Of The Cyp2w1 G541a (Ala181thr) Polymorphism With Increased Colorectal Cancer Risk
In Vivo Evaluation Of Cyp2a6 And Xanthine Oxidase Enzyme Activities In The Serbian Population
Terapéutica Y Farmacología Práctica Veterinaria, 2010-2011
In Vivo Evaluation Of Cyp2a6 And Xanthine Oxidase Enzyme Activities In The Serbian Population
Terapéutica Y Farmacología Práctica Veterinaria, 2010-2011
Chronic Haemolytic Anaemia Because Of Pyruvate Kinase (Pk) Deficiency In A Child Heterozygous For Haemoglobin S And No Clinical Features Of Sickle Cell Disease
Terapéutica Y Farmacología Práctica Veterinaria, 2010-2011
Chronic Haemolytic Anaemia Because Of Pyruvate Kinase (Pk) Deficiency In A Child Heterozygous For Haemoglobin S And No Clinical Features Of Sickle Cell Disease
N-Acetyltransferase-2 (Nat2) Gene Polymorphisms And Enzyme Activity In Serbs: Unprecedented High Prevalence Of Rapid Acetylators In A White Population.
Chronic Haemolytic Anaemia Because Of Pyruvate Kinase (Pk) Deficiency In A Child Heterozygous For Haemoglobin S And No Clinical Features Of Sickle Cell Disease
N-Acetyltransferase-2 (Nat2) Gene Polymorphisms And Enzyme Activity In Serbs: Unprecedented High Prevalence Of Rapid Acetylators In A White Population.
Polymorphisms In Methotrexate Pathways: What Is Clinically Relevant, What Is Not, And What Is Promising
N-Acetyltransferase-2 (Nat2) Gene Polymorphisms And Enzyme Activity In Serbs: Unprecedented High Prevalence Of Rapid Acetylators In A White Population.
Polymorphisms In Methotrexate Pathways: What Is Clinically Relevant, What Is Not, And What Is Promising
Promoting Appropriate Drug Use Through The Application Of The Spanish Drug-Related Problem Classification System In The Primary Care Setting
Polymorphisms In Methotrexate Pathways: What Is Clinically Relevant, What Is Not, And What Is Promising
Promoting Appropriate Drug Use Through The Application Of The Spanish Drug-Related Problem Classification System In The Primary Care Setting
A Common Polymorphism In The Bile Acid Receptor Farnesoid X Receptor Is Associated With Decreased Hepatic Target Gene Expression
Promoting Appropriate Drug Use Through The Application Of The Spanish Drug-Related Problem Classification System In The Primary Care Setting
A Common Polymorphism In The Bile Acid Receptor Farnesoid X Receptor Is Associated With Decreased Hepatic Target Gene Expression
Genetic Variability In Cyp3a4 And Cyp3a5 In Primary Liver, Gastric And Colorectal Cancer Patients
A Common Polymorphism In The Bile Acid Receptor Farnesoid X Receptor Is Associated With Decreased Hepatic Target Gene Expression
Genetic Variability In Cyp3a4 And Cyp3a5 In Primary Liver, Gastric And Colorectal Cancer Patients
Retinal Toxic Reactions Following Photopheresis
Genetic Variability In Cyp3a4 And Cyp3a5 In Primary Liver, Gastric And Colorectal Cancer Patients
Retinal Toxic Reactions Following Photopheresis
Effect Of Neurotransmitters On Nadph-Cytochrome P450 Reductase In Vitro Activity.
Retinal Toxic Reactions Following Photopheresis
Effect Of Neurotransmitters On Nadph-Cytochrome P450 Reductase In Vitro Activity.
Effect Of Common Nat2 Variant Alleles In The Acetylation Of The Major Clonazepam Metabolite, 7-Aminoclonazepam.
Effect Of Neurotransmitters On Nadph-Cytochrome P450 Reductase In Vitro Activity.
Effect Of Common Nat2 Variant Alleles In The Acetylation Of The Major Clonazepam Metabolite, 7-Aminoclonazepam.
Infection Caused By Fusarium Species In Non-Neutropenic Oncological Patients [4]
Effect Of Common Nat2 Variant Alleles In The Acetylation Of The Major Clonazepam Metabolite, 7-Aminoclonazepam.
Infection Caused By Fusarium Species In Non-Neutropenic Oncological Patients [4]
Resolution Of Disseminated Fusariosis In A Child With Acute Leukemia Treated With Combined Antifungal Therapy: A Case Report
Infection Caused By Fusarium Species In Non-Neutropenic Oncological Patients [4]
Resolution Of Disseminated Fusariosis In A Child With Acute Leukemia Treated With Combined Antifungal Therapy: A Case Report
Observation Of The Effects Of Dust Particles On Plasma Fluctuation Spectra.
Resolution Of Disseminated Fusariosis In A Child With Acute Leukemia Treated With Combined Antifungal Therapy: A Case Report
Observation Of The Effects Of Dust Particles On Plasma Fluctuation Spectra.
Adinosine Triphosphate-Binding Cassette B1 (Abcb1) (Multidrug Resistance 1) G2677t/a Gene Polymorphism Is Associated With High Risk Of Lung Cancer
Observation Of The Effects Of Dust Particles On Plasma Fluctuation Spectra.
Adinosine Triphosphate-Binding Cassette B1 (Abcb1) (Multidrug Resistance 1) G2677t/a Gene Polymorphism Is Associated With High Risk Of Lung Cancer
The Effect Of Cyp2j2, Cyp3a4, Cyp3a5 And The Mdr1 C3435t Polymorphisms And Gender On The Urinary Excretion Of The Metabolites Of The H1-Receptor Antihistamine Ebastine: A Pilot Study
Adinosine Triphosphate-Binding Cassette B1 (Abcb1) (Multidrug Resistance 1) G2677t/a Gene Polymorphism Is Associated With High Risk Of Lung Cancer
The Effect Of Cyp2j2, Cyp3a4, Cyp3a5 And The Mdr1 C3435t Polymorphisms And Gender On The Urinary Excretion Of The Metabolites Of The H1-Receptor Antihistamine Ebastine: A Pilot Study
Pharmacogenetics Of Cytochrome P450 (Cyp) 1a2 And Variability In Psychotropic Drug Response
The Effect Of Cyp2j2, Cyp3a4, Cyp3a5 And The Mdr1 C3435t Polymorphisms And Gender On The Urinary Excretion Of The Metabolites Of The H1-Receptor Antihistamine Ebastine: A Pilot Study
Pharmacogenetics Of Cytochrome P450 (Cyp) 1a2 And Variability In Psychotropic Drug Response
Differences In Cyp3a5*3 Genotype Distribution And Combinations With Other Polymorphisms Between Spaniards And Other Caucasian Populations
Pharmacogenetics Of Cytochrome P450 (Cyp) 1a2 And Variability In Psychotropic Drug Response
Differences In Cyp3a5*3 Genotype Distribution And Combinations With Other Polymorphisms Between Spaniards And Other Caucasian Populations
Evaluation Of A Drug-Drug Interaction Alert Structure Through The Retrospective Analysis Of Statins-Macrolides Co-Prescriptions
Differences In Cyp3a5*3 Genotype Distribution And Combinations With Other Polymorphisms Between Spaniards And Other Caucasian Populations
Evaluation Of A Drug-Drug Interaction Alert Structure Through The Retrospective Analysis Of Statins-Macrolides Co-Prescriptions
Polymorphisms In Human Organic Anion-Transporting Polypeptide 1a2 (Oatp1a2): Implications For Altered Drug Disposition And Central Nervous System Drug Entry
Evaluation Of A Drug-Drug Interaction Alert Structure Through The Retrospective Analysis Of Statins-Macrolides Co-Prescriptions
Polymorphisms In Human Organic Anion-Transporting Polypeptide 1a2 (Oatp1a2): Implications For Altered Drug Disposition And Central Nervous System Drug Entry
Potential Role Of Cerebral Cytochrome P450 In Clinical Pharmacokinetics: Modulation By Endogenous Compounds
Polymorphisms In Human Organic Anion-Transporting Polypeptide 1a2 (Oatp1a2): Implications For Altered Drug Disposition And Central Nervous System Drug Entry
Potential Role Of Cerebral Cytochrome P450 In Clinical Pharmacokinetics: Modulation By Endogenous Compounds
Using A Computerized Drug Prescription Screening System To Trace Drug Interactions In An Outpatient Setting
Potential Role Of Cerebral Cytochrome P450 In Clinical Pharmacokinetics: Modulation By Endogenous Compounds
Using A Computerized Drug Prescription Screening System To Trace Drug Interactions In An Outpatient Setting
Early Detection Of Drug Interactions Utilizing A Computerized Drug Prescription Handling System - Focus On Cerivastatin-Gemfibrozil
Using A Computerized Drug Prescription Screening System To Trace Drug Interactions In An Outpatient Setting
Early Detection Of Drug Interactions Utilizing A Computerized Drug Prescription Handling System - Focus On Cerivastatin-Gemfibrozil
Thrombocytopenia And Fatality Associated With Olanzapine.
Early Detection Of Drug Interactions Utilizing A Computerized Drug Prescription Handling System - Focus On Cerivastatin-Gemfibrozil
Thrombocytopenia And Fatality Associated With Olanzapine.
Thrombocytopenia And Fatality Associated With Olanzapine [2]
Thrombocytopenia And Fatality Associated With Olanzapine.
Thrombocytopenia And Fatality Associated With Olanzapine [2]
Fotoféresis: Nueva Terapia Inmunomoduladora Para Enfermedades Mediadas Por Linfocitos T.
Thrombocytopenia And Fatality Associated With Olanzapine [2]
Fotoféresis: Nueva Terapia Inmunomoduladora Para Enfermedades Mediadas Por Linfocitos T.
Photopheresis: New Immunomodulatory Therapy For T-Lymphocyte Mediated Diseases
Fotoféresis: Nueva Terapia Inmunomoduladora Para Enfermedades Mediadas Por Linfocitos T.
Photopheresis: New Immunomodulatory Therapy For T-Lymphocyte Mediated Diseases
Applicability Of An Assay For Routine Monitoring Of Highly Variable Concentrations Of Olanzapine Based On Hplc With Mass Spectrometric Detection
Photopheresis: New Immunomodulatory Therapy For T-Lymphocyte Mediated Diseases
Applicability Of An Assay For Routine Monitoring Of Highly Variable Concentrations Of Olanzapine Based On Hplc With Mass Spectrometric Detection
Genotype-Phenotype Associations For Common Cyp3a4 And Cyp3a5 Variants In The Basal And Induced Metabolism Of Midazolam In European- And African-American Men And Women
Applicability Of An Assay For Routine Monitoring Of Highly Variable Concentrations Of Olanzapine Based On Hplc With Mass Spectrometric Detection
Genotype-Phenotype Associations For Common Cyp3a4 And Cyp3a5 Variants In The Basal And Induced Metabolism Of Midazolam In European- And African-American Men And Women
Role Of The Smoking-Induced Cytochrome P450 (Cyp)1a2 And Polymorphic Cyp2d6 In Steady-State Concentration Of Olanzapine
Genotype-Phenotype Associations For Common Cyp3a4 And Cyp3a5 Variants In The Basal And Induced Metabolism Of Midazolam In European- And African-American Men And Women
Role Of The Smoking-Induced Cytochrome P450 (Cyp)1a2 And Polymorphic Cyp2d6 In Steady-State Concentration Of Olanzapine
Inhibition Of Cytochrome P450 2c9 Activity In Vitro By 5-Hydroxytryptamine And Adrenaline
Role Of The Smoking-Induced Cytochrome P450 (Cyp)1a2 And Polymorphic Cyp2d6 In Steady-State Concentration Of Olanzapine
Inhibition Of Cytochrome P450 2c9 Activity In Vitro By 5-Hydroxytryptamine And Adrenaline
Modulation Of Midazolam 1-Hydroxylation Activity In Vitro By Neurotransmitters And Precursors
Inhibition Of Cytochrome P450 2c9 Activity In Vitro By 5-Hydroxytryptamine And Adrenaline
Modulation Of Midazolam 1-Hydroxylation Activity In Vitro By Neurotransmitters And Precursors
Modulation Of Cyp1a2 Enzyme Activity By Indoleamines: Inhibition By Serotonin And Tryptamine
Modulation Of Midazolam 1-Hydroxylation Activity In Vitro By Neurotransmitters And Precursors
Modulation Of Cyp1a2 Enzyme Activity By Indoleamines: Inhibition By Serotonin And Tryptamine
Tryptamine: A Possible Endogenous Substrate For Cyp2d6
Modulation Of Cyp1a2 Enzyme Activity By Indoleamines: Inhibition By Serotonin And Tryptamine
Tryptamine: A Possible Endogenous Substrate For Cyp2d6
Aplastic Anemia During Treatment With Albendazole [8]
Tryptamine: A Possible Endogenous Substrate For Cyp2d6
Aplastic Anemia During Treatment With Albendazole [8]
Changes In Platelet Count: A Primary Or Secondary Effect Of Rhu-Epo Therapy?
Aplastic Anemia During Treatment With Albendazole [8]
Changes In Platelet Count: A Primary Or Secondary Effect Of Rhu-Epo Therapy?
Assessment Of Iron Status By Erythrocyte Ferritin In Uremic Patients With Or Without Recombinant Human Erythropoietin Therapy
Changes In Platelet Count: A Primary Or Secondary Effect Of Rhu-Epo Therapy?
Assessment Of Iron Status By Erythrocyte Ferritin In Uremic Patients With Or Without Recombinant Human Erythropoietin Therapy
Tamaño De La Fontanela En El Recién Nacido Normal. Relación Con Parámetros Antropométricos Y Bioquímicos
Assessment Of Iron Status By Erythrocyte Ferritin In Uremic Patients With Or Without Recombinant Human Erythropoietin Therapy
Tamaño De La Fontanela En El Recién Nacido Normal. Relación Con Parámetros Antropométricos Y Bioquímicos
Prognostic Significance Of Mutation Type And Chromosome Fragility In Fanconi Anemia
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