PUBLICACIÓN

Growth hormone-releasing factor regulation by somatostatin, growth hormone and insulin-like growth factor I in fetal rat hypothalamic-brain stem cell cocultures

ACCEDER A LA PUBLICACIÓN: Scopus

1993 Neuroendocrinology

CITAS

10

DOI

10.1159/000126606

EID

2-s2.0-0027718145

ISSN

0028-3835

EISSN

1423-0194

AUTORES DE LA UEX

María Jesús Lorenzo Benayas

OTRAS PUBLICACIONES DE INTERÉS

Ileal Vasoactive Intestinal Peptide (Vip) Levels And Vip Receptor/effector System In Lleal Epithelial Cells After Colectomy In The Rat
Characterization Of Autochthonal Hafnia Spp. Strains Isolated From Spanish Soft Raw Ewe's Milk Pdo Cheeses To Be Used As Adjunct Culture
Title: P38δ Regulates Il6 Expression Modulating Erk Phosphorylation In Preadipocytes
Characterization Of Autochthonal Hafnia Spp. Strains Isolated From Spanish Soft Raw Ewe's Milk Pdo Cheeses To Be Used As Adjunct Culture
Title: P38δ Regulates Il6 Expression Modulating Erk Phosphorylation In Preadipocytes
P53 Regulation By Mdm2 Contributes To Self-Renewal And Differentiation Of Basal Stem Cells In Mouse And Human Airway Epithelium
Title: P38δ Regulates Il6 Expression Modulating Erk Phosphorylation In Preadipocytes
P53 Regulation By Mdm2 Contributes To Self-Renewal And Differentiation Of Basal Stem Cells In Mouse And Human Airway Epithelium
Jnk Signaling Pathway Regulates Sorbitol-Induced Tau Proteolysis And Apoptosis In Sh-Sy5y Cells By Targeting Caspase-3
P53 Regulation By Mdm2 Contributes To Self-Renewal And Differentiation Of Basal Stem Cells In Mouse And Human Airway Epithelium
Jnk Signaling Pathway Regulates Sorbitol-Induced Tau Proteolysis And Apoptosis In Sh-Sy5y Cells By Targeting Caspase-3
Hyperosmotic Stress Induces Tau Proteolysis By Caspase-3 Activation In Sh-Sy5y Cells
Jnk Signaling Pathway Regulates Sorbitol-Induced Tau Proteolysis And Apoptosis In Sh-Sy5y Cells By Targeting Caspase-3
Hyperosmotic Stress Induces Tau Proteolysis By Caspase-3 Activation In Sh-Sy5y Cells
Implication Of Akt, Erk1/2 And Alternative P38mapk Signalling Pathways In Human Colon Cancer Cell Apoptosis Induced By Green Tea Egcg
Hyperosmotic Stress Induces Tau Proteolysis By Caspase-3 Activation In Sh-Sy5y Cells
Implication Of Akt, Erk1/2 And Alternative P38mapk Signalling Pathways In Human Colon Cancer Cell Apoptosis Induced By Green Tea Egcg
Antimicrobial Resistance Determinants Among Anaerobic Bacteria Isolated From Footrot
Implication Of Akt, Erk1/2 And Alternative P38mapk Signalling Pathways In Human Colon Cancer Cell Apoptosis Induced By Green Tea Egcg
Antimicrobial Resistance Determinants Among Anaerobic Bacteria Isolated From Footrot
Cómo Se Vive Con Un Artista
Antimicrobial Resistance Determinants Among Anaerobic Bacteria Isolated From Footrot
Cómo Se Vive Con Un Artista
Gene Context And Dna Rearrangements In The Carbapenemase Locus Of Division Ii Strains Of Bacteroides Fragilis
Cómo Se Vive Con Un Artista
Gene Context And Dna Rearrangements In The Carbapenemase Locus Of Division Ii Strains Of Bacteroides Fragilis
Genetic Determinants For Cfxa Expression In Bacteroides Strains Isolated From Human Infections
Gene Context And Dna Rearrangements In The Carbapenemase Locus Of Division Ii Strains Of Bacteroides Fragilis
Genetic Determinants For Cfxa Expression In Bacteroides Strains Isolated From Human Infections
C-Jun N-Terminal Protein Kinase Signalling Pathway Mediates Lovastatin-Induced Rat Brain Neuroblast Apoptosis
Genetic Determinants For Cfxa Expression In Bacteroides Strains Isolated From Human Infections
C-Jun N-Terminal Protein Kinase Signalling Pathway Mediates Lovastatin-Induced Rat Brain Neuroblast Apoptosis
Lovastatin Inhibits The Extracellular-Signal-Regulated Kinase Pathway In Immortalized Rat Brain Neuroblasts
C-Jun N-Terminal Protein Kinase Signalling Pathway Mediates Lovastatin-Induced Rat Brain Neuroblast Apoptosis
Lovastatin Inhibits The Extracellular-Signal-Regulated Kinase Pathway In Immortalized Rat Brain Neuroblasts
Cck1 And 2 Receptors Are Expressed In Immortalized Rat Brain Neuroblasts: Intracellular Signals After Cholecystokinin Stimulation
Lovastatin Inhibits The Extracellular-Signal-Regulated Kinase Pathway In Immortalized Rat Brain Neuroblasts
Cck1 And 2 Receptors Are Expressed In Immortalized Rat Brain Neuroblasts: Intracellular Signals After Cholecystokinin Stimulation
Cleavage Of Focal Adhesion Proteins And Pkcδ During Lovastatin-Induced Apoptosis In Spontaneously Immortalized Rat Brain Neuroblasts
Cck1 And 2 Receptors Are Expressed In Immortalized Rat Brain Neuroblasts: Intracellular Signals After Cholecystokinin Stimulation
Cleavage Of Focal Adhesion Proteins And Pkcδ During Lovastatin-Induced Apoptosis In Spontaneously Immortalized Rat Brain Neuroblasts
Erratum: Resveratrol-Induced Apoptosis In Mcf-7 Human Breast Cancer Cells Involves A Caspase-Independent Mechanism With Downregulation Of Bcl-2 And Nf-Κb (International Journal Of Cancer (2005) 115 (74-84))
Cleavage Of Focal Adhesion Proteins And Pkcδ During Lovastatin-Induced Apoptosis In Spontaneously Immortalized Rat Brain Neuroblasts
Erratum: Resveratrol-Induced Apoptosis In Mcf-7 Human Breast Cancer Cells Involves A Caspase-Independent Mechanism With Downregulation Of Bcl-2 And Nf-Κb (International Journal Of Cancer (2005) 115 (74-84))
Resveratrol-Induced Apoptosis In Mcf-7 Human Breast Cancer Cells Involves A Caspase-Independent Mechanism With Downregulation Of Bcl-2 And Nf-Κb
Erratum: Resveratrol-Induced Apoptosis In Mcf-7 Human Breast Cancer Cells Involves A Caspase-Independent Mechanism With Downregulation Of Bcl-2 And Nf-Κb (International Journal Of Cancer (2005) 115 (74-84))
Resveratrol-Induced Apoptosis In Mcf-7 Human Breast Cancer Cells Involves A Caspase-Independent Mechanism With Downregulation Of Bcl-2 And Nf-Κb
Lovastatin Inhibits The Growth And Survival Pathway Of Phosphoinositide 3-Kinase/protein Kinase B In Immortalized Rat Brain Neuroblasts
Resveratrol-Induced Apoptosis In Mcf-7 Human Breast Cancer Cells Involves A Caspase-Independent Mechanism With Downregulation Of Bcl-2 And Nf-Κb
Lovastatin Inhibits The Growth And Survival Pathway Of Phosphoinositide 3-Kinase/protein Kinase B In Immortalized Rat Brain Neuroblasts
Resveratrol Modulates The Phosphoinositide 3-Kinase Pathway Through An Estrogen Receptor Α-Dependent Mechanism: Relevance In Cell Proliferation
Lovastatin Inhibits The Growth And Survival Pathway Of Phosphoinositide 3-Kinase/protein Kinase B In Immortalized Rat Brain Neuroblasts
Resveratrol Modulates The Phosphoinositide 3-Kinase Pathway Through An Estrogen Receptor Α-Dependent Mechanism: Relevance In Cell Proliferation
Lovastatin Induces Apoptosis Of Spontaneously Immortalized Rat Brain Neuroblasts: Involvement Of Nonsterol Isoprenoid Biosynthesis Inhibition
Resveratrol Modulates The Phosphoinositide 3-Kinase Pathway Through An Estrogen Receptor Α-Dependent Mechanism: Relevance In Cell Proliferation
Lovastatin Induces Apoptosis Of Spontaneously Immortalized Rat Brain Neuroblasts: Involvement Of Nonsterol Isoprenoid Biosynthesis Inhibition
Exocytotic Protein Components In Rat Pituitary Gland After Long-Term Estrogen Administration
Lovastatin Induces Apoptosis Of Spontaneously Immortalized Rat Brain Neuroblasts: Involvement Of Nonsterol Isoprenoid Biosynthesis Inhibition
Exocytotic Protein Components In Rat Pituitary Gland After Long-Term Estrogen Administration
Direct Action Of Serotonin On Prolactin, Growth Hormone, Corticotropin And Luteinizing Hormone Release In Cocultures Of Anterior And Posterior Pituitary Lobes: Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide
Exocytotic Protein Components In Rat Pituitary Gland After Long-Term Estrogen Administration
Direct Action Of Serotonin On Prolactin, Growth Hormone, Corticotropin And Luteinizing Hormone Release In Cocultures Of Anterior And Posterior Pituitary Lobes: Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide
Ret Alternate Splicing Influences The Interaction Of Activated Ret With The Sh2 And Ptb Domains Of Shc, And The Sh2 Domain Of Grb2
Direct Action Of Serotonin On Prolactin, Growth Hormone, Corticotropin And Luteinizing Hormone Release In Cocultures Of Anterior And Posterior Pituitary Lobes: Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide
Ret Alternate Splicing Influences The Interaction Of Activated Ret With The Sh2 And Ptb Domains Of Shc, And The Sh2 Domain Of Grb2
Expression Of Multiple Endocrine Neoplasia 2b Ret In Neuroblastoma Cells Alters Cell Adhesion In Vitro, Enhances Metastatic Behavior In Vivo, And Activates Jun Kinase
Ret Alternate Splicing Influences The Interaction Of Activated Ret With The Sh2 And Ptb Domains Of Shc, And The Sh2 Domain Of Grb2
Expression Of Multiple Endocrine Neoplasia 2b Ret In Neuroblastoma Cells Alters Cell Adhesion In Vitro, Enhances Metastatic Behavior In Vivo, And Activates Jun Kinase
Regulation Of Somatostatin Gene Expression By Veratridine-Induced Depolarization In Cultured Fetal Cerebrocortical Cells
Expression Of Multiple Endocrine Neoplasia 2b Ret In Neuroblastoma Cells Alters Cell Adhesion In Vitro, Enhances Metastatic Behavior In Vivo, And Activates Jun Kinase
Regulation Of Somatostatin Gene Expression By Veratridine-Induced Depolarization In Cultured Fetal Cerebrocortical Cells
Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide On Thyrotropin-Releasing Hormone-Induced Prolactin Release
Regulation Of Somatostatin Gene Expression By Veratridine-Induced Depolarization In Cultured Fetal Cerebrocortical Cells
Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide On Thyrotropin-Releasing Hormone-Induced Prolactin Release
Autoparacrine Action Of Vasoactive Intestinal Peptide On Dopaminergic Control Of Prolactin Secretion
Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide On Thyrotropin-Releasing Hormone-Induced Prolactin Release
Autoparacrine Action Of Vasoactive Intestinal Peptide On Dopaminergic Control Of Prolactin Secretion
Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide On Thyrotropin-Releasing Hormone Induced Prolactin Release.
Autoparacrine Action Of Vasoactive Intestinal Peptide On Dopaminergic Control Of Prolactin Secretion
Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide On Thyrotropin-Releasing Hormone Induced Prolactin Release.
Autoparacrine Action Of Vasoactive Intestinal Peptide On Dopaminergic Control Of Prolactin Secretion.
Autocrine And/or Paracrine Action Of Vasoactive Intestinal Peptide On Thyrotropin-Releasing Hormone Induced Prolactin Release.
Autoparacrine Action Of Vasoactive Intestinal Peptide On Dopaminergic Control Of Prolactin Secretion.
Catalytic Specificity Of Protein-Tyrosine Kinases Is Critical For Selective Signalling
Autoparacrine Action Of Vasoactive Intestinal Peptide On Dopaminergic Control Of Prolactin Secretion.
Catalytic Specificity Of Protein-Tyrosine Kinases Is Critical For Selective Signalling
Triiodothyronine Regulates Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Catalytic Specificity Of Protein-Tyrosine Kinases Is Critical For Selective Signalling
Triiodothyronine Regulates Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Mutation Of The Ret Protooncogene In Sporadic Medullary Thyroid Carcinoma
Triiodothyronine Regulates Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Mutation Of The Ret Protooncogene In Sporadic Medullary Thyroid Carcinoma
Corticosterone Modulates Growth Hormone-Releasing Factor And Somatostatin In Fetal Rat Hypothalamic Cultures
Mutation Of The Ret Protooncogene In Sporadic Medullary Thyroid Carcinoma
Corticosterone Modulates Growth Hormone-Releasing Factor And Somatostatin In Fetal Rat Hypothalamic Cultures
Ret Activation By Germline Men2a And Men2b Mutations
Corticosterone Modulates Growth Hormone-Releasing Factor And Somatostatin In Fetal Rat Hypothalamic Cultures
Ret Activation By Germline Men2a And Men2b Mutations
Multiple Mrna Isoforms Of The Human Ret Proto-Oncogene Generated By Alternate Splicing
Ret Activation By Germline Men2a And Men2b Mutations
Multiple Mrna Isoforms Of The Human Ret Proto-Oncogene Generated By Alternate Splicing
Effect Of Potassium-Induced Depolarization On Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Multiple Mrna Isoforms Of The Human Ret Proto-Oncogene Generated By Alternate Splicing
Effect Of Potassium-Induced Depolarization On Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Induction Of Vasoactive Intestinal Peptide Gene Expression And Prolactin Secretion By Insulin-Like Growth Factor I In Rat Pituitary Cells: Evidence For An Autoparacrine Regulatory System
Effect Of Potassium-Induced Depolarization On Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Induction Of Vasoactive Intestinal Peptide Gene Expression And Prolactin Secretion By Insulin-Like Growth Factor I In Rat Pituitary Cells: Evidence For An Autoparacrine Regulatory System
Biosynthesis Of Growth Hormone-Releasing Factor By Fetal Rat Cerebrocortical And Hypothalamic Cells
Induction Of Vasoactive Intestinal Peptide Gene Expression And Prolactin Secretion By Insulin-Like Growth Factor I In Rat Pituitary Cells: Evidence For An Autoparacrine Regulatory System
Biosynthesis Of Growth Hormone-Releasing Factor By Fetal Rat Cerebrocortical And Hypothalamic Cells
Potassium-Induced Depolarization Stimulates Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Biosynthesis Of Growth Hormone-Releasing Factor By Fetal Rat Cerebrocortical And Hypothalamic Cells
Potassium-Induced Depolarization Stimulates Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Neurotransmitter Regulation Of Somatostatin Secretion By Fetal Rat Cerebral Cortical Cells In Culture
Potassium-Induced Depolarization Stimulates Somatostatin Gene Expression In Cultured Fetal Rat Cerebrocortical Cells
Neurotransmitter Regulation Of Somatostatin Secretion By Fetal Rat Cerebral Cortical Cells In Culture
Growth Hormone-Releasing Factor Regulation By Somatostatin, Growth Hormone And Insulin-Like Growth Factor I In Fetal Rat Hypothalamic-Brain Stem Cell Cocultures
Neurotransmitter Regulation Of Somatostatin Secretion By Fetal Rat Cerebral Cortical Cells In Culture
Growth Hormone-Releasing Factor Regulation By Somatostatin, Growth Hormone And Insulin-Like Growth Factor I In Fetal Rat Hypothalamic-Brain Stem Cell Cocultures
Pituitary And Peripheral Insulin‐like Growth Factor‐i Regulation By Thyroid Hormone
Growth Hormone-Releasing Factor Regulation By Somatostatin, Growth Hormone And Insulin-Like Growth Factor I In Fetal Rat Hypothalamic-Brain Stem Cell Cocultures
Pituitary And Peripheral Insulin‐like Growth Factor‐i Regulation By Thyroid Hormone
Regulation Of Somatostatin And Growth Hormone-Releasing Factor By Gonadal Steroids In Fetal Rat Hypothalamic Cells In Culture
Pituitary And Peripheral Insulin‐like Growth Factor‐i Regulation By Thyroid Hormone
Regulation Of Somatostatin And Growth Hormone-Releasing Factor By Gonadal Steroids In Fetal Rat Hypothalamic Cells In Culture
Role Of Locally Produced Growth Hormone-Releasing Factors In Somatostatin Regulatory By Fetal Rat Brain Cells In Culture
Regulation Of Somatostatin And Growth Hormone-Releasing Factor By Gonadal Steroids In Fetal Rat Hypothalamic Cells In Culture
Role Of Locally Produced Growth Hormone-Releasing Factors In Somatostatin Regulatory By Fetal Rat Brain Cells In Culture
Thyroid Hormones Regulate Release And Content Of Vasoactive Intestinal Peptide In Cultured Fetal Cerebral Cortical Cells
Role Of Locally Produced Growth Hormone-Releasing Factors In Somatostatin Regulatory By Fetal Rat Brain Cells In Culture
Thyroid Hormones Regulate Release And Content Of Vasoactive Intestinal Peptide In Cultured Fetal Cerebral Cortical Cells
Immunocytochemical Evidence Of Hypothalamic Regulation Of Adenohypophyseal Vip In The Male Rat
Thyroid Hormones Regulate Release And Content Of Vasoactive Intestinal Peptide In Cultured Fetal Cerebral Cortical Cells
Immunocytochemical Evidence Of Hypothalamic Regulation Of Adenohypophyseal Vip In The Male Rat
Endogenous Vasoactive Intestinal Peptide (Vip) Regulates Somatostatin Secretion By Cultured Fetal Rat Cerebral Cortical And Hypothalamic Cells
Immunocytochemical Evidence Of Hypothalamic Regulation Of Adenohypophyseal Vip In The Male Rat
Endogenous Vasoactive Intestinal Peptide (Vip) Regulates Somatostatin Secretion By Cultured Fetal Rat Cerebral Cortical And Hypothalamic Cells
Pineal Vasoactive Intestinal Peptide Is Reduced During The Proestrous Stage Of The Rat Estrous Cycle
Endogenous Vasoactive Intestinal Peptide (Vip) Regulates Somatostatin Secretion By Cultured Fetal Rat Cerebral Cortical And Hypothalamic Cells
Pineal Vasoactive Intestinal Peptide Is Reduced During The Proestrous Stage Of The Rat Estrous Cycle
Neurosecretory And Trophic Action On Fetal Rat Neuroblasts Induced By An Amino Acid Mixture
Pineal Vasoactive Intestinal Peptide Is Reduced During The Proestrous Stage Of The Rat Estrous Cycle
Neurosecretory And Trophic Action On Fetal Rat Neuroblasts Induced By An Amino Acid Mixture
Secretions Of Somatostatin And Vip In Cultures Of Fetal Rat Neuroblasts Increased By Amino Acids
Neurosecretory And Trophic Action On Fetal Rat Neuroblasts Induced By An Amino Acid Mixture
Secretions Of Somatostatin And Vip In Cultures Of Fetal Rat Neuroblasts Increased By Amino Acids
Demonstration Of Immunoreactive Vasoactive Intestinal Peptide (Ir-Vip) And Somatostatin (Ir-Som) In Rat Thymus
Secretions Of Somatostatin And Vip In Cultures Of Fetal Rat Neuroblasts Increased By Amino Acids
Demonstration Of Immunoreactive Vasoactive Intestinal Peptide (Ir-Vip) And Somatostatin (Ir-Som) In Rat Thymus
Influence Of Thyroid Hormones On Somatostatin Processing In Cultured Cerebro-Cortical Cells
Demonstration Of Immunoreactive Vasoactive Intestinal Peptide (Ir-Vip) And Somatostatin (Ir-Som) In Rat Thymus
Influence Of Thyroid Hormones On Somatostatin Processing In Cultured Cerebro-Cortical Cells
Depolarizing Influences Regulate Somatostatin Synthesis And Processing In Cultured Cerebral Cortical Cells
Influence Of Thyroid Hormones On Somatostatin Processing In Cultured Cerebro-Cortical Cells
Depolarizing Influences Regulate Somatostatin Synthesis And Processing In Cultured Cerebral Cortical Cells
Regulation Of The Neuropeptides, Somatostatin And Vasoactive Intestinal Peptide (Vip), By Local And External Messengers
Depolarizing Influences Regulate Somatostatin Synthesis And Processing In Cultured Cerebral Cortical Cells
Regulation Of The Neuropeptides, Somatostatin And Vasoactive Intestinal Peptide (Vip), By Local And External Messengers
Divergent Effects Of Acute Depolarization On Somatostatin Release And Protein Synthesis In Cultured Fetal And Neonatal Rat Brain Cells
Regulation Of The Neuropeptides, Somatostatin And Vasoactive Intestinal Peptide (Vip), By Local And External Messengers
Divergent Effects Of Acute Depolarization On Somatostatin Release And Protein Synthesis In Cultured Fetal And Neonatal Rat Brain Cells
Growth Hormone-Releasing Factor Production By Fetal Rat Cerebrocortical And Hypothalamic Cells In Primary Culture
Divergent Effects Of Acute Depolarization On Somatostatin Release And Protein Synthesis In Cultured Fetal And Neonatal Rat Brain Cells
Growth Hormone-Releasing Factor Production By Fetal Rat Cerebrocortical And Hypothalamic Cells In Primary Culture
Synthesis And Secretion Of Vasoactive Intestinal Peptide By Rat Fetal Cerebral Cortical And Hypothalamic Cells In Culture
Growth Hormone-Releasing Factor Production By Fetal Rat Cerebrocortical And Hypothalamic Cells In Primary Culture
Synthesis And Secretion Of Vasoactive Intestinal Peptide By Rat Fetal Cerebral Cortical And Hypothalamic Cells In Culture
Synthesis And Secretion Of Vasoactive Intestinal Peptide And Vip‐prohormone By Fetal Rat Brain Cells In Culture
Synthesis And Secretion Of Vasoactive Intestinal Peptide By Rat Fetal Cerebral Cortical And Hypothalamic Cells In Culture
Synthesis And Secretion Of Vasoactive Intestinal Peptide And Vip‐prohormone By Fetal Rat Brain Cells In Culture
Thyroid Hormone Action On Biosynthesis Of Somatostatin By Fetal Rat Brain Cells In Culture.
Synthesis And Secretion Of Vasoactive Intestinal Peptide And Vip‐prohormone By Fetal Rat Brain Cells In Culture
Thyroid Hormone Action On Biosynthesis Of Somatostatin By Fetal Rat Brain Cells In Culture.
Ileal Vasoactive Intestinal Peptide (Vip) Levels And Vip Receptor/effector System In Lleal Epithelial Cells After Colectomy In The Rat
Thyroid Hormone Action On Biosynthesis Of Somatostatin By Fetal Rat Brain Cells In Culture.
Ileal Vasoactive Intestinal Peptide (Vip) Levels And Vip Receptor/effector System In Lleal Epithelial Cells After Colectomy In The Rat
Characterization Of Autochthonal Hafnia Spp. Strains Isolated From Spanish Soft Raw Ewe's Milk Pdo Cheeses To Be Used As Adjunct Culture
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